一段超难的英语,大家翻译一下Patients: Men and nonpregnant women with hyper- cholesterolemia who were 18 years of age were included in this trial. To be eligible for randomization, all patients were required to have stable LDL ch

一段超难的英语,大家翻译一下Patients: Men and nonpregnant women with hyper- cholesterolemia who were 18 years of age were included in this trial. To be eligible for randomization, all patients were required to have stable LDL ch
一段超难的英语,大家翻译一下
Patients: Men and nonpregnant women with hyper- cholesterolemia who were 18 years of age were included in this trial. To be eligible for randomization, all patients were required to have stable LDL choles- terol concentrations of 160 and 250 mg/dl at the 2 most recent consecutive visits before randomization. Lipids were measured at up to 2 additional visits during the lead-in period if LDL cholesterol levels were not stable (measurements within 15% of each other). Triglyceride concentrations were required to be 400 mg/dl at all prerandomization visits.
Exclusion criteria included a history of sensitivity to statins; serious or unstable medical or psychological conditions that could compromise the patient’s safety or successful trial participation; a history of heterozy- gous or homozygous familial hypercholesterolemia or familial dysbetalipoproteinemia; use of concomitant medications known to affect the lipid profile or present a potential safety concern; a history of drug or alcohol abuse; unexplained increases in creatine ki- nase to 3 times the upper limit of normal during the dietary lead-in period; alanine aminotransferase (ALT), aspartate aminotransferase (AST), or bilirubin values 1.5 times the upper limit of normal during the dietary lead-in period; and participation in another investigational drug trial within 4 weeks of trial enrollment.
All participants gave informed consent before any trial procedure was initiated. The relevant institutional review boards approved the trial protocol and any amendments, and the trial was performed in accor- dance with the ethical principles consistent with good clinical practice.

一段超难的英语,大家翻译一下Patients: Men and nonpregnant women with hyper- cholesterolemia who were 18 years of age were included in this trial. To be eligible for randomization, all patients were required to have stable LDL ch
患者：男性和超胆固醇血症谁是18岁的非妊娠妇女被列入这项试验.为了获得随机的资格,所有病人都必须有在最近2连续随机访问之前低密度脂蛋白胆固醇稳定,特罗尔浓度的160和250毫克/分升.
血脂测定高达2额外访问期间率先在期间如果低密度脂蛋白胆固醇含量在15％彼此并不稳定（测量）.甘油三酯浓度必须在所有prerandomization访问400毫克/分升.
排除标准包括对敏感性他汀类药物的历史;严肃或不稳定的医疗或心理状况,可能危及病人的安全和成功的试验参与的heterozy - gous同合子家族性高胆固醇血症或家庭dysbetalipoproteinemia历史;已知伴随药物使用的影响血脂或提出一个潜在的安全问题,一个历史的药物或酒精滥用,在肌酸奇激酶不明增加到3倍正常上限的饮食中铅的期限;谷丙转氨酶（ALT）,谷草转氨酶（AST ）或胆红素的值的1.5倍正常上限的饮食中铅的时期;而在另一在4个星期的审讯报名参加的药物试验.
所有与会者通报了审判程序之前发起的同意.有关机构审查委员会批准的试验方案和任何修改,审判是在雅高与舞蹈表演,具有良好的临床实践相一致的道德原则.